FDA approves leucovorin as first drug for rare genetic disorder, after touting it as autism treatment

The move comes months after the Trump administration touted leucovorin as a potential therapy for a broader group of patients with autism symptoms.
Here are Tuesday’s biggest analyst calls: Nvidia, Apple, Microsoft, Rivian, Amazon, CrowdStrike & more

Here are Tuesday’s biggest calls on Wall Street.
How the Iran war and rising energy prices are threatening semiconductor demand

A prolonged U.S.-Israel war against Iran could lead to shortages of key chipmaking materials and higher energy costs which could hurt semiconductor demand.
Trump reiterates threat of a ‘friendly takeover’ of Cuba as fuel crisis deepens

The comments come less than a week after Trump suggested that his administration would turn its sights on Havana.
Stocks making the biggest moves premarket: Kohl’s, Casey’s General Stores, Vertex Pharmaceuticals and more

These are the stocks posting the largest moves in early trading.
Rivian is a buy ahead of R2 electric vehicle launch, says TD Cowen

Rivian Automotive’s upcoming R2 model could capitalize on an electric vehicle demand rebound in the U.S., according to TD Cowen.
Spirit Airlines to recall furloughed pilots to combat attrition as carrier eyes bankruptcy exit

Spirit Airlines is reversing course on pilot furloughs after aviators left in high numbers for rival airlines.
Iran war: Hegseth says Tuesday ‘will be our most intense day of strikes’

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Surging oil prices could wipe out benefits from Trump’s ‘big beautiful bill’

Estimates from Wall Street project that if oil prices stay elevated for too long, consumers will lose as much as they gain from the new tax law.
Oracle earnings will show whether its expensive AI bet is starting to pay off

Oracle’s $300 billion deal with OpenAI established it as a major player in AI cloud computing alongside Amazon, Google and Microsoft.